(4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone

Base Information

Chemical Name:(4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone
CAS No.:103609-06-9
Molecular Formula:C₂₉H₃₀N₂O₃
Molecular Weight:454.569
Hs Code.:

Synonyms:(4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone

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Technology Process of (4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone

There total 3 articles about (4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 3240-94-6
N-(2-chlorethyl)morpholine

: 148581-19-5
(4-Benzyloxy-phenyl)-(2-methyl-1H-indol-3-yl)-methanone

: 103609-06-9
(4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/jm00107a034

Reference yield:

: 95-20-5
2-methyl-1H-indole

: 103609-06-9
(4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) MeMgBr / 1.) Et₂O, CH₂Cl₂

2: 69 percent / K₂CO₃ / dimethylformamide

With methylmagnesium bromide; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/jm00107a034

Reference yield:

: 1486-50-6
4-(benzyloxy)benzoic acid chloride

: 103609-06-9
(4-Benzyloxy-phenyl)-[2-methyl-1-(2-morpholin-4-yl-ethyl)-1H-indol-3-yl]-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) MeMgBr / 1.) Et₂O, CH₂Cl₂

2: 69 percent / K₂CO₃ / dimethylformamide

With methylmagnesium bromide; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1021/jm00107a034