ethyl 2-nitrohexanoate

Base Information

• Chemical Name: ethyl 2-nitrohexanoate
• CAS No.: 4447-54-5
• Molecular Formula: C8H15NO4
• Molecular Weight: 189.211
• Hs Code.: 2915900090
• Mol file: 4447-54-5.mol

Synonyms:ethyl 2-nitrohexanoate

Chemical Property of ethyl 2-nitrohexanoate

Chemical Property:

• Vapor Pressure: 0.0231mmHg at 25°C
• Boiling Point: 249.3°Cat760mmHg
• Flash Point: 96°C
• PSA: 72.12000
• Density: 1.067g/cm³
• LogP: 1.90820

Purity/Quality:

98%min ^*data from raw suppliers

ETHYL-2-NITROHEXANOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl 2-nitrohexanoate

There total 11 articles about ethyl 2-nitrohexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

ethyl 2-butylacetoacetate (1540-29-0) → ethyl 2-nitrohexanoate (4447-54-5)

Guidance literature:

ethyl 2-butylacetoacetate; With sulfuric acid; nitric acid; In dichloromethane; at 10 ℃; Flow reactor;

With ethanol; at 20 ℃; Flow reactor;

DOI:10.1021/acs.joc.6b01634

Reference yield: 70.0%

ethyl 2-azidohexanoate (103999-88-8) → ethyl 2-nitrohexanoate (4447-54-5)

Guidance literature:

With HOF* CH₃CN; In chloroform; at 0 ℃;

DOI:10.1021/jo060440u

Reference yield:

Ethyl 2-bromohexanoate (615-96-3) → ethyl 2-nitrohexanoate (4447-54-5)

Guidance literature:

With 3,5-dihydroxyphenol; N,N-dimethyl-formamide; sodium nitrite;

DOI:10.1021/ja01567a041

upstream raw materials:

Ethyl 2-bromohexanoate

2-iodo-hexanoic acid ethyl ester

1-cyano-1-methylethylnitrate

Ethyl hexanoate

Downstream raw materials:

ethyl 2-n-butylacrylate

Refernces

• 1、 Stolze, Klaus,Rohr-Udilova, Natascha,Hofinger, Andreas,Rosenau, Thomas. "Spin trapping experiments with different carbamoyl-substituted EMPO derivatives". . p. 8082 - 8089. Retrieved 2008/12/23.
• 2、 Stolze, Klaus,Udilova, Natascha,Rosenau, Thomas,Hofinger, Andreas,Nohl, Hans. "Spin adduct formation from lipophilic EMPO-derived spin traps with various oxygen- and carbon-centered radicals". . p. 297 - 305. Retrieved 2007/10/03.