(R)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester

Base Information

• Chemical Name: (R)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester
• CAS No.: 1170145-06-8
• Molecular Formula: C₁₅H₁₅FO₃
• Molecular Weight: 262.281

Synonyms:(R)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester

Chemical Property of (R)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester

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Technology Process of (R)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester

There total 1 articles about (R)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H15FO3 (1170144-71-4) → (R)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester (1170145-06-8) + (S)-1-(2-fluorobenzoyl)-2-methylene-cyclopentanecarboxylic acid methyl ester

Guidance literature:

With copper(I) triflate benzene complex; 1-(3,5-bis(trifluoromethyl)phenyl)-3-((S)-quinolin-4-yl((2S,4S,8R)-8-vinylquinuclidin-2-yl)methyl)urea; In dichloromethane; at 20 ℃; for 24h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/ja9004859

upstream raw materials:

C₁₅H₁₅FO₃

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