Technology Process of methyl 4-benzyl-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate
There total 1 articles about methyl 4-benzyl-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
triphenyl phosphite; ammonium metavanadate; platinum on carbon;
In
dichloromethane;
at 20 ℃;
for 48.5h;
under 3878.71 Torr;
Reflux;
- Guidance literature:
-
methyl 4-benzyl-2-oxo-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine-7-carboxylate;
With
sodium hydride;
In
tetrahydrofuran; mineral oil;
at 20 ℃;
Inert atmosphere;
With
lithium aluminium tetrahydride;
In
tetrahydrofuran; mineral oil;
at -78 - -10 ℃;
With
methanol; water;
In
tetrahydrofuran; mineral oil;
at -78 - 20 ℃;