3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone

Base Information

• Chemical Name: 3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone
• CAS No.: 118452-62-3
• Molecular Formula: C₁₉H₂₂O₃S
• Molecular Weight: 330.448
• Mol file: 118452-62-3.mol

Synonyms:3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone

Chemical Property of 3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone

There total 2 articles about 3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

3-(4-methoxyphenyl)butan-2-one (7074-12-6) + Phenyl vinyl sulfoxide (20451-53-0) → 3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone (118452-62-3)

Guidance literature:

With sodium hydride; In benzene; Ambient temperature;

DOI:10.1002/recl.19881070404

Reference yield:

4-methoxybenzyl methyl ketone (122-84-9) → 3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone (118452-62-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 92 percent / NaH / tetrahydrofuran

2: 87 percent / NaH / benzene / Ambient temperature

With sodium hydride; In tetrahydrofuran; benzene;

DOI:10.1002/recl.19881070404

Reference yield: 26.0%

3-methyl-3-(p-methoxyphenyl)-5-(phenylsulfinyl)-2-pentanone (118452-62-3) → 3-methyl-3-(p-methoxyphenyl)-4-penten-2-one (118452-63-4)

Guidance literature:

at 180 - 200 ℃; under 0.1 Torr;

DOI:10.1002/recl.19881070404

upstream raw materials:

3-(4-methoxyphenyl)butan-2-one

Phenyl vinyl sulfoxide

4-methoxybenzyl methyl ketone

Downstream raw materials:

3-methyl-3-(p-methoxyphenyl)-4-penten-2-one

1-methoxy-4-(2-methylbut-3-en-2-yl)benzene

1-Methoxy-4-((E)-1-methyl-but-1-enyl)-benzene