Formamicin

Base Information

Chemical Name:Formamicin
CAS No.:200497-99-0
Molecular Formula:C44H72O13
Molecular Weight:809.03468
Hs Code.:
Mol file:200497-99-0.mol

Synonyms:

Suppliers and Price of Formamicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Formamicin

Chemical Property:

PSA：182.83000
LogP:5.01940

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Formamicin

There total 22 articles about Formamicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

: 749900-33-2
C₇₄H₁₄₂O₁₃Si₅

: 200497-99-0
formamicin

Guidance literature:: With triethylamine tris(hydrogen fluoride); triethylamine; In tetrahydrofuran; acetonitrile; at 20 ℃; for 336h;
DOI:10.1021/ja048493l

Reference yield:

: 251301-00-5
(2R,3S)-3-[(-O-tert-Butyldimethylsilyl)oxy]-2-methylbutan-1-ol

: 200497-99-0
formamicin

Guidance literature:: Multi-step reaction with 5 steps

1.1: 61 mg / pyridine; Dess-Martin periodinane; H₂O / CH₂Cl₂ / 23 °C

2.1: TMS-Cl; Et₃N / tetrahydrofuran / 0.17 h / -78 °C

2.2: LiHMDS / tetrahydrofuran / 0.5 h

2.3: BF₃*OEt₂ / CH₂Cl₂ / 1.33 h / -78 °C

3.1: 68 percent / SnCl₂; AgClO₄ / diethyl ether / 0.67 h / -10 °C

4.1: 94 percent / Bu₃SnH; triethylborane / toluene; hexane / 0.5 h / 20 °C

5.1: 16 percent / Et₃N*3HF; Et₃N / tetrahydrofuran; acetonitrile / 336 h / 20 °C

With pyridine; chloro-trimethyl-silane; triethyl borane; water; tri-n-butyl-tin hydride; silver perchlorate; Dess-Martin periodane; triethylamine tris(hydrogen fluoride); triethylamine; tin(ll) chloride; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; toluene; acetonitrile; 1.1: Dess-Martin oxidation / 2.3: Mukayiama aldol coupling;
DOI:10.1021/ja048493l

Reference yield:

: 6-bromo-3,4-bis-O-(tert-butyldimethylsilyl)-2,6-dideoxy-2-iodo-β-D-glucopyranosyl acetate

: 200497-99-0
formamicin

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrazine / methanol; diethyl ether; H₂O / 1.5 h / 0 °C

1.2: 78 percent / diethylaminosulfur trifluoride / CH₂Cl₂ / 0.5 h / 0 °C

2.1: 68 percent / SnCl₂; AgClO₄ / diethyl ether / 0.67 h / -10 °C

3.1: 94 percent / Bu₃SnH; triethylborane / toluene; hexane / 0.5 h / 20 °C

4.1: 16 percent / Et₃N*3HF; Et₃N / tetrahydrofuran; acetonitrile / 336 h / 20 °C

With triethyl borane; tri-n-butyl-tin hydride; silver perchlorate; triethylamine tris(hydrogen fluoride); triethylamine; tin(ll) chloride; hydrazine; In tetrahydrofuran; methanol; diethyl ether; hexane; water; toluene; acetonitrile;
DOI:10.1021/ja048493l