C₄₇H₄₇BrCl₄N₈O₁₀Si

Base Information

Chemical Name:C₄₇H₄₇BrCl₄N₈O₁₀Si
CAS No.:1370458-17-5
Molecular Formula:C₄₇H₄₇BrCl₄N₈O₁₀Si
Molecular Weight:1133.74
Hs Code.:

C<sub>47</sub>H<sub>47</sub>BrCl<sub>4</sub>N<sub>8</sub>O<sub>10</sub>Si

Synonyms:C₄₇H₄₇BrCl₄N₈O₁₀Si

Suppliers and Price of C₄₇H₄₇BrCl₄N₈O₁₀Si

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₄₇H₄₇BrCl₄N₈O₁₀Si

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of C₄₇H₄₇BrCl₄N₈O₁₀Si

There total 20 articles about C₄₇H₄₇BrCl₄N₈O₁₀Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1370458-06-2
C₅₆H₆₅BrCl₄N₈O₁₃Si

: 1370458-17-5
C₄₇H₄₇BrCl₄N₈O₁₀Si

Guidance literature:: C₅₆H₆₅BrCl₄N₈O₁₃Si; With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 4h; Cooling with ice; Inert atmosphere;

With N-ethyl-N,N-diisopropylamine; ((3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate(V); In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere; Cooling with ice;
DOI:10.1021/ol300576n

Reference yield:

: 1370458-13-1
Troc-Dap(Fmoc)-OH

: 1370458-17-5
C₄₇H₄₇BrCl₄N₈O₁₀Si

Guidance literature:: Multi-step reaction with 5 steps

1.1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / Inert atmosphere

2.1: toluene / 6.5 h / 20 - 80 °C / Inert atmosphere

3.1: diisopropylamine / acetonitrile / 20 °C / Inert atmosphere

4.1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 1 h / 0 °C / Cooling with ice; Inert atmosphere

4.2: 0 - 20 °C / Inert atmosphere

5.1: triethylsilane; trifluoroacetic acid / dichloromethane / 4 h / 20 °C / Cooling with ice; Inert atmosphere

5.2: 20 °C / Inert atmosphere; Cooling with ice

With triethylsilane; thionyl chloride; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; diisopropylamine; N,N-dimethyl-formamide; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1021/ol300576n

Reference yield:

: 1159016-08-6
methyl (S)-3-((tert-butoxycarbonyl)amino)-2-((tert-butyldiphenylsilyl)oxy)propanoate

: 1370458-17-5
C₄₇H₄₇BrCl₄N₈O₁₀Si

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydroxide / tetrahydrofuran; methanol; water / 20 °C / Cooling with ice; Inert atmosphere

2.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 1 h / 0 °C / Inert atmosphere

3.1: dichloromethane / 0 - 20 °C / Inert atmosphere

4.1: lithium hydroxide / tetrahydrofuran; water / 3 h / 20 °C / Cooling with ice

5.1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 1 h / 0 °C / Cooling with ice; Inert atmosphere

5.2: 0 - 20 °C / Inert atmosphere

6.1: triethylsilane; trifluoroacetic acid / dichloromethane / 4 h / 20 °C / Cooling with ice; Inert atmosphere

6.2: 20 °C / Inert atmosphere; Cooling with ice

With triethylsilane; 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; trifluoroacetic acid; sodium hydroxide; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/ol300576n