1-((3-(4-Methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-2-propanol

Base Information

Chemical Name:1-((3-(4-Methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-2-propanol
CAS No.:96825-87-5
Molecular Formula:C₂₂H₂₂N₄O₂
Molecular Weight:374.442
Hs Code.:
ChEMBL ID:CHEMBL24676
DSSTox Substance ID:DTXSID20914291

Synonyms:BRN 5635103;1-((3-(4-Methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-2-propanol;96825-87-5;2-Propanol, 1-((3-(4-methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-;CHEMBL24676;SCHEMBL10734791;DTXSID20914291;1-{[3-(4-Methoxyphenyl)pyridazino[4,3-c]isoquinolin-6-yl](methyl)amino}propan-2-ol

Suppliers and Price of 1-((3-(4-Methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-2-propanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-((3-(4-Methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-2-propanol

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:374.17427596
Heavy Atom Count:28
Complexity:499

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CN(C)C1=NC2=CC(=NN=C2C3=CC=CC=C31)C4=CC=C(C=C4)OC)O

Technology Process of 1-((3-(4-Methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-2-propanol

There total 5 articles about 1-((3-(4-Methoxyphenyl)pyridazino(4,3-c)isoquinolin-6-yl)methylamino)-2-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 16667-45-1
1-(methylamino)propan-2-ol

: 96825-79-5
6-Chloro-3-(4-methoxy-phenyl)-pyridazino[4,3-c]isoquinoline

: 96825-87-5
1-[[3-(4-methoxyphenyl)pyridazino-[4,3-c]-isoquinolin-6-yl]methylamino]-2-propanol

Guidance literature:: In diethylene glycol dimethyl ether; at 120 - 140 ℃; for 8h;
DOI:10.1021/jm00147a034

Reference yield:

: 96825-72-8
2-(4-Methoxy-phenyl)-10-oxa-3,4-diaza-phenanthren-9-one

: 96825-87-5
1-[[3-(4-methoxyphenyl)pyridazino-[4,3-c]-isoquinolin-6-yl]methylamino]-2-propanol

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium acetate / 9 h / 190 - 200 °C

2: 98 percent / phosphorus pentachloride, phosphorus oxychloride, pyridine / 4.5 h / Heating

3: 45 percent / bis-(2-methoxy-ethyl) ether / 8 h / 120 - 140 °C

With pyridine; ammonium acetate; phosphorus pentachloride; trichlorophosphate; In diethylene glycol dimethyl ether;
DOI:10.1021/jm00147a034

Reference yield:

: 96825-75-1
3-(4-Methoxy-phenyl)-5H-pyridazino[4,3-c]isoquinolin-6-one

: 96825-87-5
1-[[3-(4-methoxyphenyl)pyridazino-[4,3-c]-isoquinolin-6-yl]methylamino]-2-propanol

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / phosphorus pentachloride, phosphorus oxychloride, pyridine / 4.5 h / Heating

2: 45 percent / bis-(2-methoxy-ethyl) ether / 8 h / 120 - 140 °C

With pyridine; phosphorus pentachloride; trichlorophosphate; In diethylene glycol dimethyl ether;
DOI:10.1021/jm00147a034