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Technology Process of (+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide

(+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide

Base Information
  • Chemical Name:(+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide
  • CAS No.:892393-48-5
  • Molecular Formula:C28H39N5O5
  • Molecular Weight:525.648
  • Hs Code.:
(+)-N<sub>1</sub>-(cyclohexyloxycarbonyl)-N<sub>4</sub>-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide

Synonyms:(+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide

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Chemical Property of (+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide
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Technology Process of (+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide

There total 1 articles about (+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1-(3-aminophenyl)-1-(5-methyl-1H-imidazol-1-yl)methane
892393-26-9

1-(3-aminophenyl)-1-(5-methyl-1H-imidazol-1-yl)methane

N<sub>1</sub>-(cyclohexyloxycarbonyl)-N<sub>4</sub>-(tert-butoxycarbonyl)-(2R)-piperazinecarboxylic acid
279238-21-0

N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-(2R)-piperazinecarboxylic acid

(+)-N<sub>1</sub>-(cyclohexyloxycarbonyl)-N<sub>4</sub>-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide
892393-48-5

(+)-N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-N-[3-[(5-methyl-1H-imidazol-1-yl)methyl]phenyl]-(2R)-piperazine-carboxamide

Guidance literature:
With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 25 ℃; for 67h;
upstream raw materials:

1-(3-aminophenyl)-1-(5-methyl-1H-imidazol-1-yl)methane

N1-(cyclohexyloxycarbonyl)-N4-(tert-butoxycarbonyl)-(2R)-piperazinecarboxylic acid

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