(4Z)-5-(2-methylphenyl)-4-penteneoic acid

Base Information

Chemical Name:(4Z)-5-(2-methylphenyl)-4-penteneoic acid
CAS No.:1351858-96-2
Molecular Formula:C₁₂H₁₄O₂
Molecular Weight:190.242
Hs Code.:

Synonyms:(4Z)-5-(2-methylphenyl)-4-penteneoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4Z)-5-(2-methylphenyl)-4-penteneoic acid

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Technology Process of (4Z)-5-(2-methylphenyl)-4-penteneoic acid

There total 5 articles about (4Z)-5-(2-methylphenyl)-4-penteneoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 1351858-91-7
(4Z)-5-(2-methylphenyl)-4-pentenenitrile

: 1351858-96-2
(4Z)-5-(2-methylphenyl)-4-penteneoic acid

Guidance literature:: With water; sodium hydroxide; Reflux;
DOI:10.1021/ol203033k

Reference yield:

: 664341-31-5
(3-cyanopropyl)triphenylphosphonium chloride

: 1351858-96-2
(4Z)-5-(2-methylphenyl)-4-penteneoic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hexamethylsilazane / tetrahydrofuran / 0.67 h / 0 °C / Inert atmosphere

1.2: 0.5 h / 0 °C / Inert atmosphere

2.1: water; sodium hydroxide / Reflux

With water; potassium hexamethylsilazane; sodium hydroxide; In tetrahydrofuran; 1.1: Wittig reaction;
DOI:10.1021/ol203033k