HP2Ddc

Base Information

Chemical Name:HP2Ddc
CAS No.:130006-19-8
Molecular Formula:C₂₃H₂₇N₅O₅
Molecular Weight:453.498
Hs Code.:
DSSTox Substance ID:DTXSID30926562
Mol file:130006-19-8.mol

Synonyms:5',4N-bis((1,4-dihydro-1-methyl-3-pyridinyl)carbonyl)-2',3'-dideoxycytosine;HP2DDC

Suppliers and Price of HP2Ddc

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of HP2Ddc

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：109.49000
Density:1.36g/cm³
LogP:1.57880
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:453.20121898
Heavy Atom Count:33
Complexity:1010

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=CCC(=C1)C(=O)NC2=NC(=O)N(C=C2)C3CCC(O3)COC(=O)C4=CN(C=CC4)C

Technology Process of HP2Ddc

There total 3 articles about HP2Ddc which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₃H₂₅N₅O₅⁽²⁺⁾*2I^(1-)

: 130006-19-8
5',4N-bis<(1,4-dihydro-1-methyl-3-pyridinyl)carbonyl>-2',3'-dideoxycytidine

Guidance literature:: With sodium dithionite; sodium hydrogencarbonate; for 0.333333h; Yield given; Ambient temperature;
DOI:10.1021/jm00057a002

Reference yield:

: 6138-42-7
3-Carboxy-1-methylpyridiniumiodid

: 130006-19-8
5',4N-bis<(1,4-dihydro-1-methyl-3-pyridinyl)carbonyl>-2',3'-dideoxycytidine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine, N,N'-dicyclohexylcarbodiimide (DCC), 1-hydroxybenzotriazole (HOBt) / 72 h / Ambient temperature

2: aq. NaHCO₃, Na₂S₂O₄ / 0.33 h / Ambient temperature

With pyridine; sodium dithionite; sodium hydrogencarbonate; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
DOI:10.1021/jm00057a002

Reference yield:

: 7481-89-2
2`,3`-dideoxycytidine

: 130006-19-8
5',4N-bis<(1,4-dihydro-1-methyl-3-pyridinyl)carbonyl>-2',3'-dideoxycytidine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine, N,N'-dicyclohexylcarbodiimide (DCC), 1-hydroxybenzotriazole (HOBt) / 72 h / Ambient temperature

2: aq. NaHCO₃, Na₂S₂O₄ / 0.33 h / Ambient temperature

With pyridine; sodium dithionite; sodium hydrogencarbonate; benzotriazol-1-ol; dicyclohexyl-carbodiimide;
DOI:10.1021/jm00057a002