(E)-N-Boc-3-((((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)azetidine

Base Information

Chemical Name:(E)-N-Boc-3-((((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)azetidine
CAS No.:1433606-49-5
Molecular Formula:C₃₀H₃₅FN₆O₃
Molecular Weight:546.645
Hs Code.:

Synonyms:(E)-N-Boc-3-((((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)azetidine

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Chemical Property of (E)-N-Boc-3-((((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)azetidine

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Technology Process of (E)-N-Boc-3-((((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)azetidine

There total 1 articles about (E)-N-Boc-3-((((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)azetidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1433605-21-0
(E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime

: 1420859-80-8
tert-butyl 3-(2-bromoethyl)azetidine-1-carboxylate

: 1433606-49-5
(E)-N-Boc-3-((((2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-ylidene)amino)oxy)ethyl)azetidine

Guidance literature:: (E)-2-amino-7-(4-fluoro-2-(pyridin-3-yl)phenyl)-4-methyl-7,8-dihydro-6H-quinazolin-5-one oxime; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; for 0.0833333h; Inert atmosphere;

tert-butyl 3-(2-bromoethyl)azetidine-1-carboxylate; In N,N-dimethyl-formamide; mineral oil; at 60 ℃; for 1h;