4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol

Base Information

• Chemical Name: 4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol
• CAS No.: 114124-22-0
• Molecular Formula: C₁₇H₂₀O₇
• Molecular Weight: 336.342
• Mol file: 114124-22-0.mol

Synonyms:4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol

Chemical Property of 4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol

There total 1 articles about 4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.2%

phenyl chloroformate (6540-25-6) + 3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol (114124-21-9) → 4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol (114124-22-0)

Guidance literature:

In pyridine; at 4 - 5 ℃; for 72h;

DOI:10.1016/0008-6215(87)80074-5

Reference yield:

4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol (114124-22-0) → 4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-D-mannitol (114124-23-1)

Guidance literature:

In ethyl acetate; toluene; trifluoroacetic acid; for 2h; Further byproducts given. Yields of byproduct given;

DOI:10.1016/0008-6215(87)80074-5

Reference yield:

4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol (114124-22-0) → 3:1,2-O-<(R)-1-ethanyl-2-ylidene>-D-mannitol (114124-24-2) + 4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-D-mannitol (114124-23-1)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given; 1.) trifluoroacetic acid, toluene, ethylacetate, 2h; 2.) ethanol-water-M sodium hydroxide, carbon dioxide 2h;

DOI:10.1016/0008-6215(87)80074-5

upstream raw materials:

phenyl chloroformate

3:1,2-O-<(R)-1-ethanyl-2-ylidene>-5,6-O-(S)-ethylidene-D-mannitol

Downstream raw materials:

3:1,2-O-<(R)-1-ethanyl-2-ylidene>-D-mannitol

4-O-benzoyl-3:1,2-O-<(R)-1-ethanyl-2-ylidene>-D-mannitol