(E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine

Base Information

• Chemical Name: (E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine
• CAS No.: 1018832-47-7
• Molecular Formula: C₄₅H₄₆BrNO₂Si₂
• Molecular Weight: 768.941
• Mol file: 1018832-47-7.mol

Synonyms:(E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine

Chemical Property of (E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of (E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine

There total 1 articles about (E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-bromo-4,5-bis(tert-butyldiphenylsilyloxy)benzaldehyde (1018832-45-5) + triphenyl(pyridin-2-ylmethyl)phosphonium chloride hydrochloride (99662-46-1) → (E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine (1018832-47-7)

Guidance literature:

triphenyl(pyridin-2-ylmethyl)phosphonium chloride hydrochloride; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃;

3-bromo-4,5-bis(tert-butyldiphenylsilyloxy)benzaldehyde; In tetrahydrofuran; at 20 ℃; for 2h;

DOI:10.1002/chem.200800722

Reference yield: 65.0%

(E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine (1018832-47-7) → (E)-2-[(3-bromo-4,5-dihydroxyphenyl)-1-ethenyl]pyridinium chloride (1018832-48-8)

Guidance literature:

(E)-2-[3-bromo-4,5-di(tert-butyldiphenylsilyloxy)phenyl-1-ethenyl]pyridine; With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; at 0 - 20 ℃;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; for 0.166667h;

DOI:10.1002/chem.200800722

upstream raw materials:

3-bromo-4,5-bis(tert-butyldiphenylsilyloxy)benzaldehyde

triphenyl(pyridin-2-ylmethyl)phosphonium chloride hydrochloride

Downstream raw materials:

(E)-2-[(3-bromo-4,5-dihydroxyphenyl)-1-ethenyl]pyridinium chloride