(R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide

Base Information

Chemical Name:(R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide
CAS No.:952568-77-3
Molecular Formula:C₃₉H₄₂N₄O₂
Molecular Weight:598.788
Hs Code.:

Synonyms:(R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide

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Chemical Property of (R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide

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Technology Process of (R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide

There total 1 articles about (R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 947275-80-1
(R)-4-((4-benzylpiperazin-2-yl)methyl)benzonitrile

: 952568-69-3
3-(2-(2-(2-acetamidoethyl)benzyl)phenyl)propanoic acid

: 952568-77-3
(R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;

Reference yield: 98.0%

: 952568-77-3
(R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide

: 952568-76-2
(R)-4-((1-(3-(2-(2-(2-acetamidoethyl)benzyl)phenyl)propanoyl)-4-benzylpiperazin-2-yl)methyl)benzoic acid

Guidance literature:: (R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide; With water; potassium hydroxide; In methanol; at 85 ℃; for 120h; Inert atmosphere;

With hydrogenchloride; In methanol; water; at 20 ℃; Inert atmosphere;

Reference yield:

: 952568-77-3
(R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide

: C₃₉H₄₃N₇O₂

Guidance literature:: (R)-N-(2-(2-(3-(4-benzyl-2-(4-cyanobenzyl)piperazin-1-yl)-3-oxopropyl)benzyl)phenethyl)acetamide; With triethylamine hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 0.0333333h; Inert atmosphere;

With sodium azide; triethylamine hydrochloride; In N,N-dimethyl-formamide; at 90 ℃; for 22h; Inert atmosphere;