1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

Base Information

Chemical Name:1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose
CAS No.:1446906-51-9
Molecular Formula:C₃₄H₄₉NO₃Si₂
Molecular Weight:575.939
Hs Code.:

Synonyms:1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

Suppliers and Price of 1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

There total 4 articles about 1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1446906-32-6
1β-(2-bromo-6-chloropyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

: 98-80-6
phenylboronic acid

: 1446906-51-9
1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In toluene; at 100 ℃; for 12h; Inert atmosphere;
DOI:10.1039/c3ob40774h

Reference yield:

: 1446906-24-6
1β-(6-bromo-2-chloropyridin-3-yl)-1,2-dideoxy-D-ribofuranose

: 1446906-51-9
1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 14 h / 0 - 20 °C / Inert atmosphere

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / toluene / 12 h / 100 °C / Inert atmosphere

With 1H-imidazole; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In N,N-dimethyl-formamide; toluene;
DOI:10.1039/c3ob40774h

Reference yield:

: 1446906-22-4
1β-(6-bromo-2-chloropyridin-3-yl)-1,2,3-trideoxy-3-oxo-D-ribofuranose

: 1446906-51-9
1β-(2,6-diphenylpyridin-3-yl)-1,2-dideoxy-3,5-di-O-(t-butyldimethylsilyl)-D-ribofuranose

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tris(acetoxy)borohydride; acetic acid / acetonitrile / 0.08 h / 0 °C / Inert atmosphere

2: 1H-imidazole / N,N-dimethyl-formamide / 14 h / 0 - 20 °C / Inert atmosphere

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / toluene / 12 h / 100 °C / Inert atmosphere

With 1H-imidazole; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium tris(acetoxy)borohydride; potassium carbonate; acetic acid; In N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1039/c3ob40774h