(S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride

Base Information

Chemical Name:(S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride
CAS No.:1416946-42-3
Molecular Formula:C₁₃H₁₀F₄N₂*ClH
Molecular Weight:306.69
Hs Code.:

Synonyms:(S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride

Chemical Property:

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Technology Process of (S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride

There total 2 articles about (S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1416800-06-0
(S)-N-((S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methyl)-2-methylpropane-2-sulfinamide

: 1416946-42-3
(S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; ethanol; dichloromethane; at 0 ℃; for 2h;

Reference yield:

: (S)-N-((S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methyl)-2-methylpropane-2-sulfinamide

: 1416946-42-3
(S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; ethanol; dichloromethane; at 0 ℃; for 2h;

Reference yield:

: 1416946-42-3
(S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride

: 53234-55-2
5-cyano-pyridine-2-carboxylic acid

: 1416797-67-5
(S)-N₂-((3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)-methyl)pyridine-2,5-dicarboxamide

Guidance literature:: (S)-(3-fluoropyridin-2-yl)(4-(trifluoromethyl)phenyl)methanamine hydrochloride; 5-cyano-pyridine-2-carboxylic acid; With HATU; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 16h;

With sulfuric acid; water; In dichloromethane; for 5h; Cooling with ice;