2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

Base Information

Chemical Name:2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one
CAS No.:1333248-18-2
Molecular Formula:C₂₃H₂₆N₄O₃
Molecular Weight:406.484
Hs Code.:

Synonyms:2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

Suppliers and Price of 2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of 2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

There total 2 articles about 2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 13889-98-0
N-acetylpiperidine

: 903499-47-8
2-chloromethyl-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

: 1333248-18-2
2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

Guidance literature:: 2-chloromethyl-3-(2-ethoxyphenyl)quinazolin-4(3H)-one; With potassium carbonate; In ethanol; acetonitrile; at 150 ℃; for 0.0833333h; Microwave irradiation;

N-acetylpiperidine; In ethanol; acetonitrile; at 150 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1016/j.bmcl.2011.07.043

Reference yield:

: 14422-49-2
2-chloroacetamidobenzoic acid

: 1333248-18-2
2-((4-acetylpiperazin-1-yl)methyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / acetonitrile / 0.25 h / 150 °C / Microwave irradiation

2.1: potassium carbonate / ethanol; acetonitrile / 0.08 h / 150 °C / Microwave irradiation

2.2: 0.17 h / 150 °C / Microwave irradiation

With potassium carbonate; trichlorophosphate; In ethanol; acetonitrile;
DOI:10.1016/j.bmcl.2011.07.043