1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

Base Information

Chemical Name:1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline
CAS No.:1228828-73-6
Molecular Formula:C₂₈H₂₇N₃O₃S
Molecular Weight:485.607
Hs Code.:

Synonyms:1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

Suppliers and Price of 1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

There total 5 articles about 1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 635-46-1
1,2,3,4-tetrahydroisoquinoline

: C₁₉H₁₇ClN₂O₃S

: 1228828-73-6
1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 26 ℃;

Reference yield:

: 1228828-35-0
6-{(E)-2-[2-(Cyclopropylmethoxy)-3-methoxyphenyl]vinyl}imidazo[2,1-b][1,3]thiazole-5-carboxylic acid

: 1228828-73-6
1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1.5 h / 0 - 20 °C

2: triethylamine / dichloromethane / 0 - 20 °C

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;

Reference yield:

: 1228828-38-3
Ethyl 6-{(E)-2-[2-(cyclopropylmethoxy)-3-methoxyphenyl]vinyl}imidazo[2,1-b][1,3]thiazole-5-carboxylate

: 1228828-73-6
1-({6-[(E)-2-(2-Cyclopropylmethoxy-3-methoxyphenyl)vinyl]imidazo[2,1-b][1,3]thiazol-5-yl}carbonyl)-1,2,3,4-tetrahydroquinoline

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium hydroxide monohydrate; water / tetrahydrofuran / 2 h / 20 °C

1.2: pH 4

2.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 1.5 h / 0 - 20 °C

3.1: triethylamine / dichloromethane / 0 - 20 °C

With oxalyl dichloride; lithium hydroxide monohydrate; water; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;