(5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid

Base Information

Chemical Name:(5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid
CAS No.:1224444-79-4
Molecular Formula:C₂₄H₂₃ClN₃O₅P
Molecular Weight:499.89
Hs Code.:

Synonyms:(5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid

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Chemical Property of (5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid

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Technology Process of (5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid

There total 2 articles about (5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1224445-06-0
5-chloro-6-iodo-3H-1,3-benzodiazole

: 1224445-05-9
diethyl 5-hydroxy-2-methylphenylphosphonate

: 186498-02-2
4-(4-morpholinyl)phenylboronic acid

: 1224444-79-4
(5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid

Guidance literature:: 6-chloro-5-iodobenzimidazole; With sodium hydride; In N,N-dimethyl-formamide; for 0.5h; Cooling in ice;

With (2-trimethylethylsilylethoxy)methyl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

diethyl 5-hydroxy-2-methylphenylphosphonate; 4-(4-morpholinyl)phenylboronic acid;

Reference yield:

: 1224445-38-8
C₂₈H₃₁ClN₃O₅P

: 1224444-79-4
(5-(6-chloro-5-(4-morpholin-4-ylphenyl)-1H-benzo[d]imidazol-2-yloxy)-2-methylphenyl)phosphonic acid

Guidance literature:: C₂₈H₃₁ClN₃O₅P; With trimethylsilyl bromide; In dichloromethane; for 3h;

With 1,1,1,3,3,3-hexamethyl-disilazane; In dichloromethane; for 5.5h;

With trimethylsilyl bromide; In dichloromethane;