2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one

Base Information

• Chemical Name: 2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one
• CAS No.: 22794-92-9
• Molecular Formula: C₁₅H₁₁N₃O₃S
• Molecular Weight: 313.337
• Mol file: 22794-92-9.mol

Synonyms:2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one

Chemical Property of 2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one

There total 7 articles about 2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

4-Nitrophenacyl bromide (99-81-0) + Benzimidazol-2-thiol (134469-07-1) → 2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one (22794-92-9)

Guidance literature:

With potassium carbonate; In acetone; Reflux;

DOI:10.1134/S1070428021060130

Reference yield:

2-((2-(4-nitrophenyl)-2-oxoethyl)thio)-1H-benzo[d]imidazol-3-ium sulfate salt → 2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one (22794-92-9)

Guidance literature:

In water; at 20 ℃; for 2h;

DOI:10.1016/j.ejmech.2015.09.023

Reference yield:

Benzimidazol-2-thiol (134469-07-1) + (4-nitrophenyl)ethanone (100-19-6) → 2-((1H-benzo[d]imidazol-2-yl)thio)-1-(4-nitrophenyl)ethan-1-one (22794-92-9)

Guidance literature:

Benzimidazol-2-thiol; (4-nitrophenyl)ethanone; With sulfuric acid; acetic acid; for 0.5h; Reflux;

With sodium carbonate; In water; at 20 ℃; for 2h;

DOI:10.3390/ijms17081221

upstream raw materials:

(4-nitrophenyl)ethanone

4-Nitrophenacyl bromide

Benzimidazol-2-thiol

1,2-diamino-benzene

Downstream raw materials:

benzo[4,5]imidazo[2,1-b]thiazol-2-yl(nitrophenyl)methanone

3-(4-nitrophenyl)thiazolo[3,2-a]benzimidazole