5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

Base Information

Chemical Name:5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole
CAS No.:1186423-56-2
Molecular Formula:C₁₉H₁₅F₃N₂O₄S
Molecular Weight:424.4
Hs Code.:

Synonyms:5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

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Chemical Property of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

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Technology Process of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

There total 1 articles about 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

: 1186423-54-0
5-(4-cyanomethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

: 1186423-56-2
5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

Guidance literature:: With hydrogenchloride; water; In 1,4-dioxane; for 16h; Reflux;
DOI:10.1016/j.bmc.2009.05.046

Reference yield: 90.0%

: 1186423-56-2
5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

: 1186423-60-8
5-(4-chlorocarbonylmethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

Guidance literature:: With oxalyl dichloride; In dichloromethane; at 25 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.bmc.2009.05.046

Reference yield: 84.0%

: 742081-73-8
O₂-acetoxymethyl-1-[N-(2-methylsulfonyloxyethyl)-N-methylamino]diazen-1-ium-1,2-diolate

: 1186423-56-2
5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole

: 1186423-58-4
O₂-acetoxymethyl-1-{N-[2-(2-(4-(1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazol-5-yl)phenyl)acetoxy)ethyl]-N-methylamino}diazen-1-ium-1,2-diolate

Guidance literature:: 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole; With sodium carbonate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 25 ℃; for 24h;

O₂-acetoxymethyl-1-[N-(2-methylsulfonyloxyethyl)-N-methylamino]diazen-1-ium-1,2-diolate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 25 ℃; for 72h;
DOI:10.1016/j.bmc.2009.05.046