CID 16667702

Base Information

Chemical Name:CID 16667702
CAS No.:2182-14-1
Molecular Formula:C25H32N2O6
Molecular Weight:456.539
Hs Code.:29339900
European Community (EC) Number:218-558-0
Metabolomics Workbench ID:50479
NCI Thesaurus Code:C1273
Wikipedia:Vindoline
Mol file:2182-14-1.mol

Synonyms:vindoline;vindoline, citrate, (2beta,3beta,4beta,5alpha,12beta,19alpha)-isomer;vindoline, monohydrochloride, (2beta,3beta,4beta,5alpha,12beta,19alpha)-isomer

Suppliers and Price of CID 16667702

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Vindoline
20mg
$ 280.00

TRC
Vindoline
50mg
$ 275.00

DC Chemicals
Vindoline >98%,StandardReferencesGrade
20 mg
$ 280.00

ChemScene
Vindoline 99.33%
20mg
$ 140.00

ChemScene
Vindoline 99.33%
10mg
$ 80.00

ChemScene
Vindoline 99.33%
5mg
$ 50.00

Cayman Chemical
Vindoline ≥98%
50mg
$ 232.00

Cayman Chemical
Vindoline ≥98%
10mg
$ 55.00

Cayman Chemical
Vindoline ≥98%
5mg
$ 29.00

Cayman Chemical
Vindoline ≥98%
25mg
$ 131.00

Total 113 raw suppliers

Chemical Property of CID 16667702

Chemical Property:

Appearance/Colour:Off-white solid
Vapor Pressure:0mmHg at 25°C
Melting Point:163-165 °C
Refractive Index:1.626
Boiling Point:569.8 °C at 760 mmHg
PKA:5.5 in 66% DMF (Moza, Trojánek)
Flash Point:298.4 °C
PSA：88.54000
Density:1.33 g/cm³
LogP:1.64420
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:6
Exact Mass:456.22603674
Heavy Atom Count:33
Complexity:864

Purity/Quality:

99% ^*data from raw suppliers

Vindoline ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 68
Safety Statements: 36/37-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC12C=CCN3C1C4(CC3)C(C(C2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C
Isomeric SMILES:CC[C@@]12C=CCN3[C@@H]1[C@]4(CC3)C([C@]([C@@H]2OC(=O)C)(C(=O)OC)O)N(C5=C4C=CC(=C5)OC)C
Uses A novel antitumor agent Vindoline is a novel antitumor agent.

Technology Process of CID 16667702

There total 157 articles about CID 16667702 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: C₂₅H₃₀N₂O₇

: 2182-14-1
vindoline

Guidance literature:: C₂₅H₃₀N₂O₇; With 2,6-di-tert-butyl-pyridine; methyl trifluoromethanesulfonate; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

With sodium tetrahydroborate; In methanol; at 20 ℃; for 0.25h;
DOI:10.1016/j.tet.2018.11.046