Technology Process of C24H20F3N3O
There total 6 articles about C24H20F3N3O which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-(4-(trifluoromethyl)phenyl)pyridin-2(1H)-one; di-tert-butyl 8-bromo-1,2,4,5-tetrahydroazepino[4,5-b]indole-3,6-dicarboxylate;
With
8-quinolinol; caesium carbonate;
copper(l) iodide;
In
dimethyl sulfoxide;
at 135 ℃;
Inert atmosphere;
With
trifluoroacetic acid;
In
water; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 0.5 h / Inert atmosphere
2: acetic anhydride / 5 h / 140 °C
3: caesium carbonate; 8-quinolinol / copper(l) iodide / dimethyl sulfoxide / 135 °C / Inert atmosphere
With
8-quinolinol; acetic anhydride; potassium carbonate; caesium carbonate;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) iodide;
In
dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogenchloride / ethanol; water / Reflux
1.2: 2 h / 25 °C
2.1: caesium carbonate; 8-quinolinol / copper(l) iodide / dimethyl sulfoxide / 135 °C / Inert atmosphere
With
hydrogenchloride; 8-quinolinol; caesium carbonate;
copper(l) iodide;
In
ethanol; water; dimethyl sulfoxide;