C₂₈H₃₂FN₃O₂Si

Base Information

Chemical Name:C₂₈H₃₂FN₃O₂Si
CAS No.:1198274-33-7
Molecular Formula:C₂₈H₃₂FN₃O₂Si
Molecular Weight:489.665
Hs Code.:

C<sub>28</sub>H<sub>32</sub>FN<sub>3</sub>O<sub>2</sub>Si

Synonyms:C₂₈H₃₂FN₃O₂Si

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Chemical Property of C₂₈H₃₂FN₃O₂Si

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Technology Process of C₂₈H₃₂FN₃O₂Si

There total 7 articles about C₂₈H₃₂FN₃O₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1198273-71-0
6-[2-(tert-Butyldimethylsilanyloxymethyl)-3-fluorophenyl]-2-chloroimidazo[1,2-a]pyridine

: 78887-39-5
3-Acetamidophenylboronic acid

: 1198274-33-7
C₂₈H₃₂FN₃O₂Si

Guidance literature:: With potassium phosphate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; In ethanol; toluene; at 75 ℃; for 26h; Inert atmosphere;

Reference yield:

: 827614-64-2
2-aminopyridine-5-boronic acid pinacol ester

: 1198274-33-7
C₂₈H₃₂FN₃O₂Si

Guidance literature:: Multi-step reaction with 4 steps

1: 20 h / 20 °C

2: trichlorophosphate / 16 h / 105 °C

3: caesium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran; water / 2 h / Inert atmosphere; Heating

4: potassium phosphate / dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate / ethanol; toluene / 26 h / 75 °C / Inert atmosphere

With potassium phosphate; caesium carbonate; trichlorophosphate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; palladium diacetate; In tetrahydrofuran; ethanol; water; toluene;

Reference yield:

: 360575-28-6
2-bromo-6-fluorobenzaldehyde

: 1198274-33-7
C₂₈H₃₂FN₃O₂Si

Guidance literature:: Multi-step reaction with 4 steps

1: methanol; sodium tetrahydroborate / 1 h / Cooling with ice

2: 1H-imidazole / tetrahydrofuran / 16 h

3: caesium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / tetrahydrofuran; water / 2 h / Inert atmosphere; Heating

4: potassium phosphate / dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate / ethanol; toluene / 26 h / 75 °C / Inert atmosphere

With 1H-imidazole; methanol; sodium tetrahydroborate; potassium phosphate; caesium carbonate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; palladium diacetate; In tetrahydrofuran; ethanol; water; toluene;