N'-[(E)-[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-(4-phenyl-1,3-thiazol-2-yl)propanediamide

Base Information

Chemical Name:N'-[(E)-[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-(4-phenyl-1,3-thiazol-2-yl)propanediamide
CAS No.:18612-35-6
Molecular Formula:C₂₃H₂₃Cl₂N₅O₂S
Molecular Weight:504.44
Hs Code.:
NSC Number:82372

Synonyms:NSC82372;18612-35-6;NSC-82372

Suppliers and Price of N'-[(E)-[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-(4-phenyl-1,3-thiazol-2-yl)propanediamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N'-[(E)-[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-(4-phenyl-1,3-thiazol-2-yl)propanediamide

Chemical Property:

Density:1.34g/cm³
XLogP3:5.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:11
Exact Mass:503.0949516
Heavy Atom Count:33
Complexity:636

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)CC(=O)NN=CC3=CC=C(C=C3)N(CCCl)CCCl
Isomeric SMILES:C1=CC=C(C=C1)C2=CSC(=N2)NC(=O)CC(=O)N/N=C/C3=CC=C(C=C3)N(CCCl)CCCl

Technology Process of N'-[(E)-[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-(4-phenyl-1,3-thiazol-2-yl)propanediamide

There total 2 articles about N'-[(E)-[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-N-(4-phenyl-1,3-thiazol-2-yl)propanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71638-89-6
N-(4-phenyl-thiazol-2-yl)-malonamic acid ethyl ester

: 18612-35-6
N-(4-phenyl-thiazol-2-yl)-malonamic acid {4-[bis-(2-chloro-ethyl)-amino]-benzylidene}-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: N₂H₄*H₂O / ethanol / 0.17 h / Heating

2: ethanol / 70 °C

With hydrazine hydrate; In ethanol;
DOI:10.1021/jm00307a037