enkephalin-Leu, cyclo-N(gamma)-diNH-butyryl-

Base Information

Chemical Name:enkephalin-Leu, cyclo-N(gamma)-diNH-butyryl-
CAS No.:77171-72-3
Molecular Formula:C30H40 N6 O6
Molecular Weight:580.68
Hs Code.:
Mol file:77171-72-3.mol

Synonyms:L-Leucine,L-tyrosyl-D-a,g-diaminobutyrylglycyl-L-phenylalanyl-,cyclic (5®2)-peptide;1,4,7,10-Tetraazacyclotetradecane, cyclic peptide deriv.

Suppliers and Price of enkephalin-Leu, cyclo-N(gamma)-diNH-butyryl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of enkephalin-Leu, cyclo-N(gamma)-diNH-butyryl-

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:946°C at 760 mmHg
Flash Point:525.9°C
PSA：191.75000
Density:1.206g/cm³
LogP:2.04770

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of enkephalin-Leu, cyclo-N(gamma)-diNH-butyryl-

There total 6 articles about enkephalin-Leu, cyclo-N(gamma)-diNH-butyryl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [(S)-1-((3S,6S,12R)-6-Benzyl-3-isobutyl-2,5,8,11-tetraoxo-1,4,7,10-tetraaza-cyclotetradec-12-ylcarbamoyl)-2-(4-hydroxy-phenyl)-ethyl]-carbamic acid benzyl ester

: 77171-72-3
H-Tyr-cyclo<-N^γ-D-A2bu-Gly-Phe-Leu->

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; for 10h; under 1034.3 Torr;
DOI:10.1021/jm00354a008

Reference yield:

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 77171-72-3
H-Tyr-cyclo<-N^γ-D-A2bu-Gly-Phe-Leu->

Guidance literature:: Multi-step reaction with 5 steps

2: Et₃N, diphenyl phosphoroazidate (DPPA) / dimethylformamide / 24 h

3: Na/liquid NH₃

4: Et₃N, 1-(ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline (EEDQ) / dimethylformamide / 18 h

5: H₂, 50percent aq. AcOH / 5percent Pd/C / 10 h / 1034.3 Torr

With diphenyl phosphoryl azide; ammonia; hydrogen; sodium; acetic acid; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1021/jm00354a008

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 77171-72-3
H-Tyr-cyclo<-N^γ-D-A2bu-Gly-Phe-Leu->

Guidance literature:: Multi-step reaction with 5 steps

2: Et₃N, diphenyl phosphoroazidate (DPPA) / dimethylformamide / 24 h

3: Na/liquid NH₃

4: Et₃N, 1-(ethoxycarbonyl)-2-ethoxy-1,2-dihydroquinoline (EEDQ) / dimethylformamide / 18 h

5: H₂, 50percent aq. AcOH / 5percent Pd/C / 10 h / 1034.3 Torr

With diphenyl phosphoryl azide; ammonia; hydrogen; sodium; acetic acid; N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline; triethylamine; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1021/jm00354a008