Boc-Tyr-Pro-Trp-PheNH₂

Base Information

Chemical Name:Boc-Tyr-Pro-Trp-PheNH₂
CAS No.:351184-02-6
Molecular Formula:C₃₉H₄₆N₆O₇
Molecular Weight:710.83
Hs Code.:

Synonyms:Boc-Tyr-Pro-Trp-PheNH₂

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Chemical Property of Boc-Tyr-Pro-Trp-PheNH₂

Chemical Property:

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Technology Process of Boc-Tyr-Pro-Trp-PheNH₂

There total 10 articles about Boc-Tyr-Pro-Trp-PheNH₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.5%

: 74201-47-1,124194-60-1,124194-61-2
(tert-butoxycarbonyl)-L-tyrosyl-L-proline

: 158276-61-0
2-amino-N-(1-amino-1-oxo-3-phenylpropan-2-yl)-3-(1H-indol-3-yl)propanamide

: 351184-02-6
Boc-Tyr-Pro-Trp-PheNH₂

Guidance literature:: With Pseudomonas aeruginosa PT₁₂₁ protease; In water; ethyl acetate; at 35 ℃; for 12h; Enzymatic reaction;
DOI:10.1039/c1gc15042a

Reference yield:

: 3978-80-1
Boc-Tyr-OH

: H-Pro-Trp-PheNH₂ hydrochloride

: 351184-02-6
Boc-Tyr-Pro-Trp-PheNH₂

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 12h;
DOI:10.1039/b301507f

Reference yield:

: 13139-14-5
Boc-Trp-OH

: 351184-02-6
Boc-Tyr-Pro-Trp-PheNH₂

Guidance literature:: Multi-step reaction with 5 steps

1: Et₃N; HOBt; EDCI / CH₂Cl₂; dimethylformamide / 12 h / 0 °C

2: HCl / dioxane / 1 h / 0 °C

3: Et₃N; HOBt; EDCI / CH₂Cl₂; dimethylformamide / 12 h / 0 °C

4: HCl / dioxane / 1 h / 0 °C

5: Et₃N; HOBt; EDCI / CH₂Cl₂; dimethylformamide / 12 h / 0 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/b301507f