Technology Process of methyl 6-(benzyloxy)-4-methylhexa-2,3-dienoate
There total 5 articles about methyl 6-(benzyloxy)-4-methylhexa-2,3-dienoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; sodium methylate;
In
methanol;
at 20 ℃;
for 48h;
Inert atmosphere;
DOI:10.1021/ol300111m
- Guidance literature:
-
Multi-step reaction with 4 steps
1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C
3: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 0.5 h / 0 °C
4: 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; sodium methylate / methanol / 48 h / 20 °C / Inert atmosphere
With
n-butyllithium; 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; tetrabutyl ammonium fluoride; sodium methylate; sodium hydrogencarbonate; Dess-Martin periodane;
In
tetrahydrofuran; methanol; hexane; dichloromethane;
DOI:10.1021/ol300111m
- Guidance literature:
-
Multi-step reaction with 3 steps
1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 °C
2: sodium hydrogencarbonate; Dess-Martin periodane / dichloromethane / 0.5 h / 0 °C
3: 3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; sodium methylate / methanol / 48 h / 20 °C / Inert atmosphere
With
3-mesityl-4,5,6,7-tetrahydrobenzo[d]thiazol-3-ium perchlorate; tetrabutyl ammonium fluoride; sodium methylate; sodium hydrogencarbonate; Dess-Martin periodane;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ol300111m
