1-(4-Fluoro-2-nitrophenyl)ethanone

Base Information

Chemical Name:1-(4-Fluoro-2-nitrophenyl)ethanone
CAS No.:1214346-44-7
Molecular Formula:C₈H₆FNO₃
Molecular Weight:183.139
Hs Code.:9999999999
European Community (EC) Number:835-585-9
DSSTox Substance ID:DTXSID10607408
Wikidata:Q82506420

Synonyms:1-(4-Fluoro-2-nitrophenyl)ethanone;1214346-44-7;1-(4-fluoro-2-nitrophenyl)ethan-1-one;4'-FLUORO-2'-NITROACETOPHENONE;Ethanone, 1-(4-fluoro-2-nitrophenyl)-;SCHEMBL621197;AMY6689;DTXSID10607408;MFCD13194367;DB-389670;CS-0089132;EN300-133067

Suppliers and Price of 1-(4-Fluoro-2-nitrophenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
1-(4-Fluoro-2-nitrophenyl)ethanone
1g
$ 1507.00

Alichem
4'-Fluoro-2'-nitroacetophenone
250mg
$ 470.40

Alichem
4'-Fluoro-2'-nitroacetophenone
500mg
$ 823.15

Crysdot
1-(4-Fluoro-2-nitrophenyl)ethanone 97%
1g
$ 880.00

TRC
1-(4-Fluoro-2-nitrophenyl)ethanone
5mg
$ 45.00

Total 7 raw suppliers

Chemical Property of 1-(4-Fluoro-2-nitrophenyl)ethanone

Chemical Property:

Boiling Point:301.2±22.0 °C(Predicted)
Density:1.336±0.06 g/cm3(Predicted)
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:183.03317122
Heavy Atom Count:13
Complexity:226

Purity/Quality:

97% ^*data from raw suppliers

1-(4-Fluoro-2-nitrophenyl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=C(C=C(C=C1)F)[N+](=O)[O-]

Technology Process of 1-(4-Fluoro-2-nitrophenyl)ethanone

There total 4 articles about 1-(4-Fluoro-2-nitrophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1262802-07-2
(E)-1-(4-fluoro-2-nitrophenyl)ethanone O-methyl oxime

: 1214346-44-7
1-(4-fluoro-2-nitrophenyl)ethanone

Guidance literature:: With hydrogenchloride; water; In diethyl ether; at 20 ℃; for 24h;
DOI:10.1002/chem.201002581

Reference yield:

: (E)-1-(4-fluorophenyl)ethan-1-one O-methyl oxime

: 1214346-44-7
1-(4-fluoro-2-nitrophenyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: silver(I) nitrite; dipotassium peroxodisulfate; palladium diacetate / 1,2-dichloro-ethane / 48 h / 130 °C / sealed tube

2: hydrogenchloride; water / diethyl ether / 24 h / 20 °C

With hydrogenchloride; dipotassium peroxodisulfate; silver(I) nitrite; water; palladium diacetate; In diethyl ether; 1,2-dichloro-ethane;
DOI:10.1002/chem.201002581

Reference yield:

: 403-42-9
1-(4-fluorophenyl)ethanone

: 1214346-44-7
1-(4-fluoro-2-nitrophenyl)ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / methanol / Reflux

2: silver(I) nitrite; dipotassium peroxodisulfate; palladium diacetate / 1,2-dichloro-ethane / 48 h / 130 °C / sealed tube

3: hydrogenchloride; water / diethyl ether / 24 h / 20 °C

With pyridine; hydrogenchloride; dipotassium peroxodisulfate; silver(I) nitrite; water; palladium diacetate; In methanol; diethyl ether; 1,2-dichloro-ethane;
DOI:10.1002/chem.201002581