[1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester

Base Information

• Chemical Name: [1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester
• CAS No.: 123176-11-4
• Molecular Formula: C₂₅H₂₅N₅O₆S
• Molecular Weight: 523.569
• Mol file: 123176-11-4.mol

Synonyms:[1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester

Chemical Property of [1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester

There total 1 articles about [1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

[1-(2-Amino-thiazol-4-yl)-1-((S)-2,2-dimethyl-4-oxo-1-sulfooxy-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester (123176-10-3) → [1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester (123176-11-4)

Guidance literature:

With water; In tetrahydrofuran; for 45h; Ambient temperature;

DOI:10.1002/jhet.5570260104

Reference yield: 53.0%

[1-(2-Amino-thiazol-4-yl)-1-((S)-1-hydroxy-2,2-dimethyl-4-oxo-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester (123176-11-4) → <4S(Z)>-<<<1-(2-amino-4-thiazolyl)-2-<(3,3-dimethyl-5-oxo-4-isoxazolidinyl)amino>-2-oxoethylidene>amino>oxy>acetic acid, diphenylmethyl ester (123191-09-3)

Guidance literature:

With triethylamine; In ethyl acetate; for 30h; Product distribution; Heating;

DOI:10.1002/jhet.5570260104

upstream raw materials:

[1-(2-Amino-thiazol-4-yl)-1-((S)-2,2-dimethyl-4-oxo-1-sulfooxy-azetidin-3-ylcarbamoyl)-meth-(Z)-ylideneaminooxy]-acetic acid benzhydryl ester

Downstream raw materials:

<4S(Z)>-<<<1-(2-amino-4-thiazolyl)-2-<(3,3-dimethyl-5-oxo-4-isoxazolidinyl)amino>-2-oxoethylidene>amino>oxy>acetic acid, diphenylmethyl ester