4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

Base Information

Chemical Name:4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide
CAS No.:758672-64-9
Molecular Formula:C₂₃H₁₉F₃N₂O
Molecular Weight:396.412
Hs Code.:

Synonyms:4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

Suppliers and Price of 4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

There total 3 articles about 4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 256395-30-9
carbamic acid, [2,3-dihydro-5-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1H-inden-2-yl]-, methyl ester

: 758672-64-9
4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

Guidance literature:: With trimethylsilyl iodide; In acetonitrile; at 20 ℃;
DOI:10.1021/jm010294e

Reference yield:

: 84392-17-6
4'-(trifluoromethyl)-2-biphenylcarboxylic acid

: 758672-64-9
4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl chloride; DMF / CH₂Cl₂ / 16 h / 20 °C

2: pyridine / CH₂Cl₂ / 0.25 h

3: Me₃SiI / acetonitrile / 20 °C

With pyridine; oxalyl dichloride; trimethylsilyl iodide; N,N-dimethyl-formamide; In dichloromethane; acetonitrile;
DOI:10.1021/jm010294e

Reference yield:

: 180340-74-3
4'-trifluoromethylbiphenyl-2-carbonyl chloride

: 758672-64-9
4'-trifluoromethyl-biphenyl-2-carboxylic acid (2-amino-indan-5-yl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂ / 0.25 h

2: Me₃SiI / acetonitrile / 20 °C

With pyridine; trimethylsilyl iodide; In dichloromethane; acetonitrile;
DOI:10.1021/jm010294e