N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

Base Information

Chemical Name:N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide
CAS No.:1059549-38-0
Molecular Formula:C₂₉H₃₉FN₈O₆S
Molecular Weight:646.743
Hs Code.:

N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

Synonyms:N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

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Technology Process of N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

There total 1 articles about N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1059549-37-9
3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzoic acid

: 1059549-02-8
C₁₄H₂₅N₅O₄*ClH

: 1059549-38-0
N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In water; N,N-dimethyl-formamide; at 0 ℃; for 2h;

Reference yield:

: 1059549-38-0
N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

: 1059549-39-1
N-[1(S)-((3aS,6aS)-6(R)-azido-3-oxohexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide

: N-[1(S)-((3aS,6aS)-6(R)-azido-3-oxohexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide hydrate

Guidance literature:: N-[1(S)-((3aS,6aS)-6(R)-azido-3,3-dimethoxyhexahydrofuro[3,2-b]pyrrole-4-carbonyl)-3-methylbutyl]-3-fluoro-4-[2-(4-methyl-4-oxypiperazin-1-yl)thiazol-4-yl]benzamide; With water; trifluoroacetic acid; for 2h;

With sodium hydrogencarbonate; In acetonitrile; for 1h;