3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

Base Information

Chemical Name:3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide
CAS No.:1186421-60-2
Molecular Formula:C₂₇H₂₂N₆O₂S
Molecular Weight:494.577
Hs Code.:

Synonyms:3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

Suppliers and Price of 3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

There total 5 articles about 3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 1186422-01-4
3-(3-iodo-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

: 220465-43-0
indole-4-boronic acid

: 1186421-60-2
3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

Guidance literature:: With potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; water; at 80 ℃; for 3h; Inert atmosphere;

Reference yield:

: 173158-15-1
3-acetyl-N,N-dimethylbenzenesulfonamide

: 1186421-60-2
3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: 100 °C

2: acetic acid / 3.5 h / 80 °C

3: N-iodo-succinimide / chloroform / 4.5 h / 20 °C

4: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; water / 3 h / 80 °C / Inert atmosphere

With N-iodo-succinimide; potassium carbonate; acetic acid; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; chloroform; water; 4: Suzuki Coupling;

Reference yield:

: 1186421-98-6
N,N-dimethyl-3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)benzenesulfonamide

: 1186421-60-2
3-(3-(1H-indol-4-yl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)-N,N-dimethylbenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: N-iodo-succinimide / chloroform / 4.5 h / 20 °C

2: potassium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,2-dimethoxyethane; water / 3 h / 80 °C / Inert atmosphere

With N-iodo-succinimide; potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In 1,2-dimethoxyethane; chloroform; water; 2: Suzuki Coupling;