Frenolicin

Base Information

Chemical Name:Frenolicin
CAS No.:10023-07-1
Molecular Formula:C₁₈H₁₈O₇
Molecular Weight:346.337
Hs Code.:
UNII:H1POH9E7JP
DSSTox Substance ID:DTXSID20433578
Nikkaji Number:J15.788K
Wikidata:Q27279511
Metabolomics Workbench ID:128941
ChEMBL ID:CHEMBL2409149
Mol file:10023-07-1.mol

Synonyms:frenolicin;frenolicin B

Suppliers and Price of Frenolicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Frenolicin

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:655.774°C at 760 mmHg
Flash Point:243.284°C
Density:1.51g/cm³
XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:346.10525291
Heavy Atom Count:25
Complexity:631

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1C23C(=O)C4=C(C=CC=C4O)C(=O)C2(O3)CC(O1)CC(=O)O
Isomeric SMILES:CCC[C@@H]1[C@]23C(=O)C4=C(C=CC=C4O)C(=O)[C@]2(O3)C[C@H](O1)CC(=O)O

Technology Process of Frenolicin

There total 14 articles about Frenolicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 73794-56-6,77448-22-7
(7S,7aS,9R,11S,11aS,11bR)-2,2-Dimethyl-11-propyl-7,8,9,11,11a,11b-hexahydro-7aH-1,3,10-trioxa-benzo[de]anthracene-7,9-diol

: 10023-07-1,73804-51-0,77448-38-5,77549-95-2
(+/-)-frenolicin

Guidance literature:: Multi-step reaction with 6 steps

1: 60.9 percent / n-Buli / dimethylsulfoxide / 2 h / Ambient temperature

2: 98.2 percent / pyridinium chlorochromate / CH₂Cl₂ / Ambient temperature

3: 80 percent / DDQ, TsOH / methanol / Heating; 9h, addn. of dioxane, 12h

4: KOH / methanol; H₂O

5: 1.) t.BuOOh, Triton B / 1.) dioxane, ethanol, r.t.

6: KOH / methanol; H₂O / Ambient temperature

With tert.-butylhydroperoxide; potassium hydroxide; n-butyllithium; N-benzyl-trimethylammonium hydroxide; toluene-4-sulfonic acid; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In methanol; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1016/S0040-4039(00)92203-2

Reference yield:

: 1450893-33-0
frenolicin F

: 10023-07-1,73804-51-0,77448-38-5,77549-95-2
(-)-frenolicin

Guidance literature:: With Dess-Martin periodane; In chloroform-d1; at 20 ℃; for 0.166667h;
DOI:10.1021/np400231r

Reference yield:

: 73794-56-6,77448-22-7
(7S,7aS,9R,11S,11aS,11bR)-2,2-Dimethyl-11-propyl-7,8,9,11,11a,11b-hexahydro-7aH-1,3,10-trioxa-benzo[de]anthracene-7,9-diol

: 10023-07-1,73804-51-0,77448-38-5,77549-95-2
(+/-)-epifrenolicin

Guidance literature:: Multi-step reaction with 5 steps

1: 60.9 percent / n-Buli / dimethylsulfoxide / 2 h / Ambient temperature

2: 98.2 percent / pyridinium chlorochromate / CH₂Cl₂ / Ambient temperature

3: 80 percent / DDQ, TsOH / methanol / Heating; 9h, addn. of dioxane, 12h

4: KOH / methanol; H₂O

5: t-BuOOH, Triton B / dioxane; H₂O / Ambient temperature

With tert.-butylhydroperoxide; potassium hydroxide; n-butyllithium; N-benzyl-trimethylammonium hydroxide; toluene-4-sulfonic acid; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; methanol; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1016/S0040-4039(00)92203-2