Deoxyribose 1-phosphate

Base Information

• Chemical Name: Deoxyribose 1-phosphate
• CAS No.: 17210-42-3
• Molecular Formula: C₅H₁₁O₇P
• Molecular Weight: 214.112
• DSSTox Substance ID: DTXSID601308825
• Nikkaji Number: J2.128.155G
• Wikidata: Q27103763
• Metabolomics Workbench ID: 37742
• Mol file: 17210-42-3.mol

Synonyms:2-deoxy-alpha-D-ribose 1-phosphate;2-deoxyribose 1-phosphate;2-deoxyribose 1-phosphate, (alpha-D-erythro)-isomer;2-deoxyribose 1-phosphate, (beta-D-erythro)-isomer

Chemical Property of Deoxyribose 1-phosphate

Chemical Property:

• Vapor Pressure: 2.45E-13mmHg at 25°C
• Boiling Point: 527.6°Cat760mmHg
• PKA: 1.72±0.10(Predicted)
• Flash Point: 272.9°C
• PSA: 126.26000
• Density: 1.72g/cm³
• LogP: -1.43610
• XLogP3: -2.1
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 3
• Exact Mass: 214.02423968
• Heavy Atom Count: 13
• Complexity: 213

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1C(C(OC1OP(=O)(O)O)CO)O
• Isomeric SMILES: C1[C@@H]([C@H](OC1OP(=O)(O)O)CO)O

Technology Process of Deoxyribose 1-phosphate

There total 5 articles about Deoxyribose 1-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-Iodo-2'-deoxyuridine (54-42-2,162239-35-2) → 2-deoxyribofuranose-1-phosphate (17039-17-7,17112-88-8,18684-29-2,17210-42-3) + 5-iodouracil (696-07-1)

Guidance literature:

With recombinant thymidine phosphorylase from Mycoplasma hyorhinis; at 37 ℃; for 0.333333h; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1042/BJ20112225

Reference yield:

5-Fluoro-2'-deoxyuridine (50-91-9) → 5-fluorouracil (51-21-8) + 2-deoxyribofuranose-1-phosphate (17039-17-7,17112-88-8,18684-29-2,17210-42-3)

Guidance literature:

With recombinant thymidine phosphorylase from Mycoplasma hyorhinis; at 37 ℃; for 0.333333h; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1042/BJ20112225

Reference yield:

uridine (58-96-8) → 2-deoxyribofuranose-1-phosphate (17039-17-7,17112-88-8,18684-29-2,17210-42-3) + uracil (66-22-8,144104-68-7,18324-22-6,27072-01-1,2920-92-5,51953-19-6)

Guidance literature:

With human uridine phosphorylase (UP); In water; at 20 ℃; Conversion of starting material; Enzymatic reaction; Aqueous phosphate buffer;

upstream raw materials:

thymidine

5-Fluoro-2'-deoxyuridine

uridine

5-Iodo-2'-deoxyuridine

Refernces

• 1、 -. "PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2 ' - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER". Page/Page column 66-67. . Retrieved 2012/09/21.