1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole

Base Information

• Chemical Name: 1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole
• CAS No.: 273730-83-9
• Molecular Formula: C₁₀H₁₀N₄O₂S
• Molecular Weight: 250.281
• Mol file: 273730-83-9.mol

Synonyms:1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole

Chemical Property of 1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole

There total 2 articles about 1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-phenyl-5-(2-propen-1-ylthio)-1H-tetrazole (119784-86-0) → 1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole (273730-83-9)

Guidance literature:

With ammonium molybdate tetrahydrate; dihydrogen peroxide; In ethanol; at 0 ℃; for 8h;

DOI:10.1021/jo801338t

Reference yield:

1-Phenyl-1H-tetrazole-5-thiol (86-93-1) → 1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole (273730-83-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / paraffin oil; tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

1.2: 0 - 25 °C / Inert atmosphere

2.1: ammonium molybdate; dihydrogen peroxide / ethanol / 0 - 25 °C / Inert atmosphere

With ammonium molybdate; dihydrogen peroxide; sodium hydride; In tetrahydrofuran; ethanol; paraffin oil;

DOI:10.1039/d1ob02126e

Reference yield: 57.0%

C26H32O3Si + 1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole (273730-83-9) → (1'Z,1''E,3''E,2S,3R,4S)-2-(buta-1',3'-dienyl)-3-(tert-butyldiphenylsilanyloxy)-4-(penta-1'',3''-dienyl)tetrahydrofuran (1065271-67-1) + (1'E,1''E,3''E,2S,3R,4S)-2-(buta-1',3'-dienyl)-3-(tert-butyldiphenylsilanyloxy)-4-(penta-1'',3''-dienyl)tetrahydrofuran (1065271-65-9)

Guidance literature:

1-phenyl-5-(prop-2'-ene-1'-sulfonyl)-1H-tetrazole; With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -78 ℃; for 0.5h;

C₂₆H₃₂O₃Si; In tetrahydrofuran; toluene; at -78 ℃; for 1h; Further stages.;

DOI:10.1021/jo801338t

upstream raw materials:

1-phenyl-5-(2-propen-1-ylthio)-1H-tetrazole

1-Phenyl-1H-tetrazole-5-thiol

Downstream raw materials:

(1'Z,1''E,3''E,2S,3R,4S)-2-(buta-1',3'-dienyl)-3-(tert-butyldiphenylsilanyloxy)-4-(penta-1'',3''-dienyl)tetrahydrofuran

(1'E,1''E,3''E,2S,3R,4S)-2-(buta-1',3'-dienyl)-3-(tert-butyldiphenylsilanyloxy)-4-(penta-1'',3''-dienyl)tetrahydrofuran

(Z)-hexa-3,5-dien-1-ylbenzene

(E)-hexa-3,5-dien-1-ylbenzene