sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

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Chemical Name:sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
CAS No.:1016968-26-5
Molecular Formula:C₃₁H₃₉FN₃O₆S*Na
Molecular Weight:623.721
Hs Code.:

Synonyms:sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

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Chemical Property of sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

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Technology Process of sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

There total 4 articles about sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1041640-68-9
C₃₁H₃₈FN₃O₅S

: 1016968-26-5
sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

Guidance literature:: With sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 4h;
DOI:10.1016/j.bmcl.2007.11.124

Reference yield:

: 110417-50-0
1-methyl-4-[(2-phenylethynyl)sulfonyl]piperazine

: 1016968-26-5
sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

Guidance literature:: Multi-step reaction with 3 steps

1: acetic anhydride / toluene / 5 h / 60 °C

2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

3: sodium hydroxide / tetrahydrofuran / 4 h / 20 °C

With acetic anhydride; trifluoroacetic acid; sodium hydroxide; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1089/adt.2017.804

Reference yield:

: C₃₆H₄₈FN₃O₈S

: 1016968-26-5
sodium (3R,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-4-((4-methylpiperazin-1-yl)sulfonyl)-3-phenyl-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate

Guidance literature:: Multi-step reaction with 2 steps

1: trifluoroacetic acid / dichloromethane / 2 h / 20 °C

2: sodium hydroxide / tetrahydrofuran / 4 h / 20 °C

With trifluoroacetic acid; sodium hydroxide; In tetrahydrofuran; dichloromethane;
DOI:10.1089/adt.2017.804