(S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

Base Information

Chemical Name:(S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide
CAS No.:1582806-48-1
Molecular Formula:C₃₀H₁₇F₇N₂O₃
Molecular Weight:586.465
Hs Code.:

Synonyms:(S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

Suppliers and Price of (S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

Chemical Property:

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Technology Process of (S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

There total 12 articles about (S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 591-50-4
iodobenzene

: 1582806-47-0
(S)-3-phenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propanamide

: 1582806-48-1
(S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

Guidance literature:: With palladium(II) trifluoroacetate; 3,4-dihydro-2,5-dimethyl-2H-pyrano<2,3-b>quinoline; silver carbonate; trifluoroacetic acid; In 1,2-dichloro-ethane; at 100 ℃; for 20h; Reagent/catalyst;
DOI:10.1126/science.1249198

Reference yield:

: 591-50-4
iodobenzene

: 1582806-46-9
(S)-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propanamide

: 1582806-47-0
(S)-3-phenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propanamide

: 1582806-48-1
(S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

Guidance literature:: With 2,6-dimethylpyridine; palladium(II) trifluoroacetate; silver carbonate; trifluoroacetic acid; In 1,2-dichloro-ethane; at 100 ℃; for 20h; Reagent/catalyst;
DOI:10.1126/science.1249198

Reference yield:

: 1582806-46-9
(S)-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)propanamide

: 1582806-48-1
(S)-3,3-diphenyl-2-phthalimido-N-(2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl)ropanamide

Guidance literature:: Multi-step reaction with 2 steps

1: α-picoline; palladium(II) trifluoroacetate; trifluoroacetic acid; silver carbonate / 1,2-dichloro-ethane / 20 h / 100 °C

2: palladium(II) trifluoroacetate; trifluoroacetic acid; silver carbonate; 3,4-dihydro-2,5-dimethyl-2H-pyrano<2,3-b>quinoline / 1,2-dichloro-ethane / 20 h / 100 °C

With α-picoline; palladium(II) trifluoroacetate; 3,4-dihydro-2,5-dimethyl-2H-pyrano<2,3-b>quinoline; silver carbonate; trifluoroacetic acid; In 1,2-dichloro-ethane;
DOI:10.1126/science.1249198