4-((2-Chloroethyl)(ethyl)amino)-2-methylbenzaldehyde

Base Information

• Chemical Name: 4-((2-Chloroethyl)(ethyl)amino)-2-methylbenzaldehyde
• CAS No.: 92-10-4
• Molecular Formula: C12H16 Cl N O
• Molecular Weight: 225.718
• Hs Code.: 2922399090
• European Community (EC) Number: 202-125-8
• DSSTox Substance ID: DTXSID9059040
• Nikkaji Number: J60.299J
• Wikidata: Q72450081
• Mol file: 92-10-4.mol

Synonyms:92-10-4;4-((2-Chloroethyl)(ethyl)amino)-2-methylbenzaldehyde;4-[2-chloroethyl(ethyl)amino]-2-methylbenzaldehyde;EINECS 202-125-8;4-((2-CHLOROETHYL)ETHYLAMINO)-2-METHYLBENZALDEHYDE;4-((2-Chloroethyl)ethylamino)-o-tolualdehyde;4-(2-chloroethyl-ethylamino)-2-methylbenzaldehyde;4-(N-Ethyl-N-chloroethyl)amino-2-methyl benzaldehyde;Benzaldehyde, 4-[(2-chloroethyl)ethylamino]-2-methyl-;4-[(2-chloroethyl)ethylamino]-o-tolualdehyde;Benzaldehyde, 4-((2-chloroethyl)ethylamino)-2-methyl-;4-[(2-Chloroethyl)ethylamino]-2-methylbenzaldehyde;SCHEMBL9513863;DTXSID9059040;AKOS015890439;4-[(2-chlorethyl)ethylamino]-o-tolualdehyd;FT-0652074;A844147;N-ethyl-N-chloroethyl-4-amino-2-methyl benzaldehyde;4-[2-chloroethyl(ethyl)amino]-2-methyl-benzaldehyde;4-(N-ETHYL-N-CHLOROETHYL)AMINO-2-METHYLBENZALDEHYDE;4-(N-(2-CHLOROETHYL)-N-ETHYLAMINO)-2-METHYLBENZALDEHYDE

Chemical Property of 4-((2-Chloroethyl)(ethyl)amino)-2-methylbenzaldehyde

Chemical Property:

• Vapor Pressure: 1.5E-05mmHg at 25°C
• Boiling Point: 366.1oC at 760 mmHg
• Flash Point: 175.2oC
• PSA: 20.31000
• Density: 1.129g/cm3
• LogP: 2.87260
• Storage Temp.: 2-8°C
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 225.0920418
• Heavy Atom Count: 15
• Complexity: 198

Purity/Quality:

97% ^*data from raw suppliers

4-(N-ETHYL-N-CHLOROETHYL)AMINO-2-METHYL BENZALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CCCl)C1=CC(=C(C=C1)C=O)C

Technology Process of 4-((2-Chloroethyl)(ethyl)amino)-2-methylbenzaldehyde

There total 2 articles about 4-((2-Chloroethyl)(ethyl)amino)-2-methylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-[ethyl-(2-chloro-ethyl)-amino]-2-methyl-benzaldehyde (92-10-4)

Guidance literature:

With trichlorophosphate; Erwaermen des Reaktionsgemisches mit N-Methyl-formanilid und Phosphoroxychlorid;

Reference yield:

→ 4-[ethyl-(2-chloro-ethyl)-amino]-2-methyl-benzaldehyde (92-10-4)

Guidance literature:

3-Me-4-HCO-C6H3-NEt-CH2CH2OH, POCl3;

Reference yield: 65.0%

2,3-dimethylanthrapyridinium methylsulfate (77544-32-2) + 4-[ethyl-(2-chloro-ethyl)-amino]-2-methyl-benzaldehyde (92-10-4) → C30H28ClN2O(1+)*CH3O4S(1-) (77544-46-8)

Guidance literature:

With piperidine; In acetic anhydride; for 0.5h; Heating;

DOI:10.1007/BF00507251

Downstream raw materials:

C₃₀H₂₈ClN₂O⁽¹⁺⁾*CH₃O₄S^(1-)

Methyl 2-cyano-3-[4-[2[[4-(2-cyano-3-methoxy-3-oxo-1-propenyl)-3-methylphenyl]ethylamino]ethoxy]-3-methoxyphenyl]propenoate

Refernces

A concise α-amino acid-based synthetic approach to [1,4]oxazepin-2-ones from Baylis-Hillman adducts

10.1016/j.tetlet.2009.01.048

The research aims to develop a novel two-step synthetic process for the creation of [1,4]oxazepin-2-ones, a family of chemically and pharmacologically interesting compounds, starting from Baylis–Hillman (BH) adducts. The study successfully demonstrated that this operationally simple method, performed under ambient conditions, yields 81–93% of the target [1,4]oxazepin-2-ones, thereby opening up new synthetic utility for BH adducts. Key chemicals used in the process include BH adducts, a-amino esters, and various catalysts, with KOH proving to be the most effective catalyst. The research concludes that this approach not only provides an efficient method for synthesizing 1,4-oxazepines but also highlights the potential for extending this methodology to other amino acid-derived chiral heterocycles.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 92-10-4 4-((2-Chloroethyl)ethylamino)-2-methylbenzaldehyde

Send

Send

Metric Ton KG G Pound L ML

Send

Send