5,7-dibenzyloxyindole

Base Information

• Chemical Name: 5,7-dibenzyloxyindole
• CAS No.: 50545-14-7
• Molecular Formula: C₂₂H₁₉NO₂
• Molecular Weight: 329.398
• Mol file: 50545-14-7.mol

Synonyms:5,7-dibenzyloxyindole

Chemical Property of 5,7-dibenzyloxyindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,7-dibenzyloxyindole

There total 3 articles about 5,7-dibenzyloxyindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

3,5-Di(benzyloxy)-2,β-dinitrostyrol (50545-13-6) → 5,7-dibenzyloxyindole (50545-14-7)

Guidance literature:

With silica gel; iron; In toluene; for 1h; Heating;

DOI:10.1021/jo00167a045

Reference yield:

tris(piperidino)-methane (22630-08-6) + 3,5-bis(benzyloxy)-2-nitrotoluene → 5,7-dibenzyloxyindole (50545-14-7)

Guidance literature:

With iron; silica gel; Yield given. Multistep reaction; 1) 120 deg C under vacuum 2) 1 h reflux in toluene-acetic acid;

Reference yield:

→ 5,7-dibenzyloxyindole (50545-14-7)

Guidance literature:

3,5-Di(benzyloxy)-2,β-dinitrostyryl, Fe/Aethanol/HOAc;

upstream raw materials:

tris(piperidino)-methane

3,5-Di(benzyloxy)-2,β-dinitrostyrol

Downstream raw materials:

(5,7-Bis-benzyloxy-1H-indol-3-yl)-oxo-acetyl chloride

(5,7-Bis-benzyloxy-1H-indol-3-yl)-oxo-acetic acid