(Z)-methyl 4-(1,2-diphenylvinyl)benzoate

Base Information

• Chemical Name: (Z)-methyl 4-(1,2-diphenylvinyl)benzoate
• CAS No.: 1337965-07-7
• Molecular Formula: C₂₂H₁₈O₂
• Molecular Weight: 314.384
• Mol file: 1337965-07-7.mol

Synonyms:(Z)-methyl 4-(1,2-diphenylvinyl)benzoate

Chemical Property of (Z)-methyl 4-(1,2-diphenylvinyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-methyl 4-(1,2-diphenylvinyl)benzoate

There total 8 articles about (Z)-methyl 4-(1,2-diphenylvinyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxycarbonylphenyl bromide (619-42-1) + (E)-1-(4',4',5',5'-tetramethyl-1’,3’,2’-dioxaborolan-2’-yl)-1,2-diphenylethene (1391743-16-0) → (Z)-methyl 4-(1,2-diphenylvinyl)benzoate (1337965-07-7)

Guidance literature:

With potassium phosphate; bis[tris( 1,1-dimethylethyl)phosphine]-palladium; In 1,2-dimethoxyethane; water; at 80 ℃; for 12h;

DOI:10.1021/acscatal.7b02104

Reference yield:

(E)-1,2-diphenyl-ethene (103-30-0) + methyl 4-iodobenzoate (619-44-3) → (E)-methyl 4-(1,2-diphenylvinyl)benzoate (1020073-97-5) + (Z)-methyl 4-(1,2-diphenylvinyl)benzoate (1337965-07-7)

Guidance literature:

With silver(I) acetate; palladium diacetate; acetic acid; at 110 ℃; for 0.5h; optical yield given as %de;

DOI:10.1016/j.tet.2011.12.017

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → (Z)-methyl 4-(1,2-diphenylvinyl)benzoate (1337965-07-7)

Guidance literature:

Multi-step reaction with 3 steps

1: ethanol; (^tBuPNN)CoCl₂; sodium triethylborohydride / toluene / 12 h / 20 °C

2: palladium diacetate; potassium hydroxide; johnphos / N,N-dimethyl-formamide / 12 h / 30 °C

3: potassium phosphate; bis[tris( 1,1-dimethylethyl)phosphine]-palladium / 1,2-dimethoxyethane; water / 12 h / 80 °C

With potassium phosphate; bis[tris( 1,1-dimethylethyl)phosphine]-palladium; ethanol; (^tBuPNN)CoCl₂; palladium diacetate; sodium triethylborohydride; potassium hydroxide; johnphos; In 1,2-dimethoxyethane; water; N,N-dimethyl-formamide; toluene;

DOI:10.1021/acscatal.7b02104

upstream raw materials:

diphenyl acetylene

4-methoxycarbonylphenylboronic acid

styrene

iodobenzene