N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

Base Information

Chemical Name:N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride
CAS No.:1020086-21-8
Molecular Formula:C₂₇H₂₃N₇O*ClH
Molecular Weight:497.987
Hs Code.:

Synonyms:N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

Suppliers and Price of N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

There total 6 articles about N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 611-35-8
4-chloroquinoline

: 1020087-06-2
4-amino-N-[4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl]benzamide hydrochloride

: 1020086-21-8
N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

Guidance literature:: With hydrogenchloride; In ethanol; water; for 3h; Reflux;
DOI:10.1016/j.bmc.2013.03.033

Reference yield:

: 100-01-6,104810-17-5
4-nitro-aniline

: 1020086-21-8
N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: hydrogenchloride / water; 2-ethoxy-ethanol / 0.5 h / Reflux

2: acetic acid; iron / water; ethanol / 14 h / Reflux

3: pyridine / 1,4-dioxane / 120 h / 50 °C

4: iron; hydrogenchloride / water; ethanol / 24 h / Reflux

5: hydrogenchloride / water; ethanol / 3 h / Reflux

With pyridine; hydrogenchloride; iron; acetic acid; In 1,4-dioxane; 2-ethoxy-ethanol; ethanol; water;
DOI:10.1016/j.bmc.2013.03.033

Reference yield:

: 20719-42-0
6-methyl-N⁴-(4-nitrophenyl)-2,4-diamino-pyrimidine

: 1020086-21-8
N-(4-(2-amino-6-methylpyrimidin-4-ylamino)phenyl)-4-(quinolin-4-ylamino)benzamide hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid; iron / water; ethanol / 14 h / Reflux

2: pyridine / 1,4-dioxane / 120 h / 50 °C

3: iron; hydrogenchloride / water; ethanol / 24 h / Reflux

4: hydrogenchloride / water; ethanol / 3 h / Reflux

With pyridine; hydrogenchloride; iron; acetic acid; In 1,4-dioxane; ethanol; water;
DOI:10.1016/j.bmc.2013.03.033