1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine

Base Information

• Chemical Name: 1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine
• CAS No.: 263762-44-3
• Molecular Formula: C₂₅H₄₀N₂O₁₂
• Molecular Weight: 560.599
• Mol file: 263762-44-3.mol

Synonyms:1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine

Chemical Property of 1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine

There total 1 articles about 1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

6-(tert-butoxycarbonylamino)hexanoic acid (6404-29-1) + 2,3,4,6-tetra-O-Acetyl-β-D-galactopyranosyl isothiocyanate (14152-97-7,18866-59-6,93221-21-7,121959-10-2,121959-11-3,122564-52-7,41135-18-6) → 1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine (263762-44-3)

Guidance literature:

With triethylamine; In toluene; at 20 ℃; for 48h;

DOI:10.1016/S0040-4039(99)02216-9

Reference yield:

1N-(tert-butoxycarbonyl-6-aminohexanoyl)-2,3,4,6-tetra-O-acetyl-β-D-galactopyranosylamine (263762-44-3) → N-(ε-aminocaproyl)-β-D-galactopyranosylamine (38822-56-9,52116-51-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOH / methanol

2: TFA

With sodium hydroxide; trifluoroacetic acid; In methanol; 1: Deacetylation / 2: deacylation;

DOI:10.1016/S0040-4039(99)02216-9

upstream raw materials:

6-(tert-butoxycarbonylamino)hexanoic acid

2,3,4,6-tetra-O-Acetyl-β-D-galactopyranosyl isothiocyanate

Downstream raw materials:

N-(ε-aminocaproyl)-β-D-galactopyranosylamine