2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

Base Information

Chemical Name:2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide
CAS No.:921630-12-8
Molecular Formula:C₃₅H₄₁Cl₃N₂O₄
Molecular Weight:660.081
Hs Code.:

Synonyms:2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

Suppliers and Price of 2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

There total 6 articles about 2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1056555-41-9
tert-butyl (2-(4-(2-(4-allyl-2,6-dichlorophenoxy)ethoxy)benzyl)-3-((2-chloro-5-(3-methoxypropyl)benzyl)(cyclopropyl)amino)-3-oxopropyl)carbamate

: 921630-12-8
2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; dichloromethane; at 20 ℃; for 4h;

Reference yield:

: 162462-12-6
2-cyano-3-[4-(2-hydroxyethoxy)phenyl]acrylic acid ethyl ester

: 921630-12-8
2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrogen / platinum(IV) oxide / ethanol / 2585.81 Torr

2.1: lithium hydroxide; ethanol; water / tetrahydrofuran / 48 h / 20 °C

2.2: pH ~ 2

3.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 18 h / 20 °C

4.1: potassium carbonate / acetone / 21 h / 160 °C / Heating / reflux

4.2: 3 h / 80 °C

5.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 4 h / 20 °C

With hydrogenchloride; lithium hydroxide; ethanol; water; hydrogen; potassium carbonate; N-ethyl-N,N-diisopropylamine; HATU; platinum(IV) oxide; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;

Reference yield:

: 22042-73-5
4-(2-hydroxy-ethoxy)-benzaldehyde

: 921630-12-8
2-{4-[2-(4-allyl-2,6-dichlorophenoxy)ethoxy]benzyl}-3-amino-N-[2-chloro-5-(3-methoxypropyl)benzyl]-N-cyclopropylpropanamide

Guidance literature:: Multi-step reaction with 6 steps

1.1: ethanol / 48 h / 20 °C

2.1: hydrogen / platinum(IV) oxide / ethanol / 2585.81 Torr

3.1: lithium hydroxide; ethanol; water / tetrahydrofuran / 48 h / 20 °C

3.2: pH ~ 2

4.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 18 h / 20 °C

5.1: potassium carbonate / acetone / 21 h / 160 °C / Heating / reflux

5.2: 3 h / 80 °C

6.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 4 h / 20 °C

With hydrogenchloride; lithium hydroxide; ethanol; water; hydrogen; potassium carbonate; N-ethyl-N,N-diisopropylamine; HATU; platinum(IV) oxide; In tetrahydrofuran; 1,4-dioxane; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone;