2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt

Base Information

• Chemical Name: 2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt
• CAS No.: 945671-66-9
• Molecular Formula: C₂HF₃O₂*C₁₇H₃₀N₂O₃
• Molecular Weight: 424.461

Synonyms:2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt

Chemical Property of 2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt

Chemical Property:

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Technology Process of 2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt

There total 1 articles about 2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C22H38N2O5 + trifluoroacetic acid (76-05-1) → 2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt (945671-66-9)

Guidance literature:

In dichloromethane; for 2h;

Reference yield:

2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt (945671-66-9) + 4-(5,6,7,8-tetrahydro[1,8]naphthyridin-2-yl)propionyl acid (658712-81-3) → C28H42N4O4

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 5h;

Reference yield:

(8-N-Boc-5,6,7,8-tetrahydro[1,8]naphthyridin-2-yl)acetic acid (445492-19-3) + 2-[(1-methylcyclohexanecarbonyl)amino]-3-piperidin-4-yl-propionic acid methyl ester trifluoroacetic acid salt (945671-66-9) → C32H48N4O6

Guidance literature:

With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 15h;

upstream raw materials:

trifluoroacetic acid

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