Benzmalecene

Base Information

• Chemical Name: Benzmalecene
• CAS No.: 148-07-2
• Molecular Formula: C₂₀H₁₉Cl₂NO₃
• Molecular Weight: 392.282
• Mol file: 148-07-2.mol

Synonyms:Maleamicacid, N-[2,3-bis(p-chlorophenyl)-1-methylpropyl]-, a-(?à)- (8CI); Benzmalecen; Benzmalecene; Benzomalecene; MK 135

Chemical Property of Benzmalecene

Chemical Property:

• Vapor Pressure: 5.05E-15mmHg at 25°C
• Boiling Point: 595.4°Cat760mmHg
• Flash Point: 313.9°C
• PSA: 69.89000
• Density: 1.302g/cm³
• LogP: 5.30550

Purity/Quality:

98%min ^*data from raw suppliers

BENZMALECENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzmalecene

There total 1 articles about Benzmalecene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (E)-3-[2,3-Bis-(4-chloro-phenyl)-1-methyl-propylcarbamoyl]-acrylic acid (148-07-2,13445-07-3)

Guidance literature:

/BRN= 593541/ II, 1) Raney-Nickel (Hydrierung), 2) Maleinsaeure-anhydrid;

Reference yield:

(E)-3-[2,3-Bis-(4-chloro-phenyl)-1-methyl-propylcarbamoyl]-acrylic acid (148-07-2,13445-07-3) → (+)-3,4-Diphenyl-2-butanone oxime

Guidance literature:

Multi-step reaction with 4 steps

1: aq. HCl, AcOH

3: H₂, KOAc / Pd-C

4: (i) N-chloro-succinimide, (ii) /BRN= 3592982/, (iii) NH₂OH*HCl, NaOAc

With hydrogenchloride; hydrogen; potassium acetate; acetic acid; palladium on activated charcoal;

DOI:10.1021/jm00316a044

Reference yield:

(E)-3-[2,3-Bis-(4-chloro-phenyl)-1-methyl-propylcarbamoyl]-acrylic acid (148-07-2,13445-07-3) → d-(+)-α-2,3-Diphenyl-1-methylpropylamin

Guidance literature:

Multi-step reaction with 3 steps

1: aq. HCl, AcOH

3: H₂, KOAc / Pd-C

With hydrogenchloride; hydrogen; potassium acetate; acetic acid; palladium on activated charcoal;

DOI:10.1021/jm00316a044