m-Nitro-α,α-difluoracetophenon

Base Information

Chemical Name:m-Nitro-α,α-difluoracetophenon
CAS No.:657-17-0
Molecular Formula:C₈H₅F₂NO₃
Molecular Weight:201.129
Hs Code.:

Synonyms:m-Nitro-α,α-difluoracetophenon

Suppliers and Price of m-Nitro-α,α-difluoracetophenon

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of m-Nitro-α,α-difluoracetophenon

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of m-Nitro-α,α-difluoracetophenon

There total 3 articles about m-Nitro-α,α-difluoracetophenon which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: C₁₅H₉F₆N₃O₄S

: 657-17-0
m-Nitro-α,α-difluoracetophenon

Guidance literature:: With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; water; N-ethyl-N,N-diisopropylamine; In chloroform; at 25 ℃; for 18h; chemoselective reaction; Sealed tube; Glovebox; Inert atmosphere;
DOI:10.1002/anie.202116190

Reference yield:

: 657-15-8
2,2,2-trifluoro-1-(3-nitrophenyl)ethanone

: 657-17-0
m-Nitro-α,α-difluoracetophenon

Guidance literature:: Multi-step reaction with 2 steps

1: ethyl acetate / 12 h / 40 °C / Acidic conditions

2: bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; N-ethyl-N,N-diisopropylamine; water / chloroform / 18 h / 25 °C / Sealed tube; Glovebox; Inert atmosphere

With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; water; N-ethyl-N,N-diisopropylamine; In chloroform; ethyl acetate;
DOI:10.1002/anie.202116190