(2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester

Base Information

Chemical Name:(2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester
CAS No.:114658-44-5
Molecular Formula:C₁₅H₁₉NO₆
Molecular Weight:309.319
Hs Code.:

Synonyms:(2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester

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Chemical Property of (2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester

Chemical Property:

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Technology Process of (2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester

There total 1 articles about (2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 114658-42-3
(S)-Benzyloxycarbonylamino-((S)-3-methyl-4,5-dihydro-isoxazol-5-yl)-acetic acid methyl ester

: 114658-44-5
(2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester

Guidance literature:: With hydrogen; boric acid; nickel; In methanol; water;
DOI:10.1246/cl.1987.2229

Reference yield:

: 114658-44-5
(2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester

: 114681-13-9,114718-40-0
(2S,3S)-3-Hydroxy-5-methyl-pyrrolidine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂/10percent Pd-C / ethanol

2: NaBH₃CN / ethanol / pH 5

With palladium on activated charcoal; hydrogen; sodium cyanoborohydride; In ethanol;
DOI:10.1246/cl.1987.2229

Reference yield:

: 114658-44-5
(2S,3S)-2-Benzyloxycarbonylamino-3-hydroxy-5-oxo-hexanoic acid methyl ester

: 114717-04-3
(2S,3S,5R)-3-hydroxy-5-methylproline

Guidance literature:: Multi-step reaction with 3 steps

1: H₂/10percent Pd-C / ethanol

2: NaBH₃CN / ethanol / pH 5

3: Ba(OH)2 / 4 h / 20 °C

With barium dihydroxide; palladium on activated charcoal; hydrogen; sodium cyanoborohydride; In ethanol;
DOI:10.1246/cl.1987.2229