(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate

Base Information

Chemical Name:(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate
CAS No.:17772-67-7
Molecular Formula:C₂₃H₂₅N₃O₆
Molecular Weight:439.468
Hs Code.:

Synonyms:(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate

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Chemical Property of (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate

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Technology Process of (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate

There total 2 articles about (S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1145-80-8
N-(benzyloxycarbonyl)-L-serine

: 4299-70-1
L-tryptophan methyl ester

: 17772-67-7
(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate

Guidance literature:: With benzotriazol-1-ol; dicyclohexyl-carbodiimide;
DOI:10.1021/ja00094a008

Reference yield: 58.0%

: 1145-80-8
N-(benzyloxycarbonyl)-L-serine

: 7524-52-9,26988-71-6,5619-09-0,14907-27-8,41222-70-2,67557-19-1,109492-62-8
(S)-tryptophan methyl ester hydrochloride

: 17772-67-7
(S)-methyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-hydroxypropanamido)-3-(1H-indol-3-yl)propanoate

Guidance literature:: N-(benzyloxycarbonyl)-L-serine; (S)-tryptophan methyl ester hydrochloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; Inert atmosphere;

With benzotriazol-1-ol; 1,2-dichloro-ethane; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.3762/bjoc.12.74